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KMID : 1007420140120030186
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Mood and Emotion
2014 Volume.12 No. 3 p.186 ~ p.191
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The Diagnostic Changes of DSM-IV-TR Major Depressive Disorder with Psychotic Features in Korean Patients
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Oh Seung-Young
Kang Won-Sub
Paik Jong-Woo
Bahn Geon-Ho
Song Ji-Young
Kim Jong-Woo
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Abstract
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Objectives : Several studies suggested that major depressive disorder (MDD) with psychotic features might be a distinct disease in several clinical features. Therefore, we investigated the clinical features of the inpatients with MDD with psychotic features at a university hospital in Korea.
Method : We performed a retrospective analysis of 79 patients who had ever been hospitalized as DSM-IV-TR MDD with psychotic features in a University Hospital from 2002 to 2012. We investigated and analyzed several clinical aspects, such as diagnostic changes, concomitant psychotic symptoms, family histories, and suicidal attempts from the medical records of the patients.
Results : Among 79 patients whose initial diagnoses were MDD, 70 (88.6%) were not changed, 6 (7.6%) shifted to Bipolar disorder and 3 (3.8%) shifted to Schizophrenia. In the two groups, persisting MDD and shifting to other diagnoses, significant differences were found in the follow-up duration and the number of hospitalization. In the whole patients, 35 patients (44.3%) had hallucinations, 70 patients (88.6%) had delusions, 25 patients (31.6%) had family histories and 38 patients (48.1%) had suicidal ideations.
Conclusion : The diagnostic stability of MDD with psychotic features was slightly higher than previous researches. The follow-up duration and the number of hospitalization were significant predictors associated with diagnostic shift.
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KEYWORD
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Major depressive disorder, Psychotic features, Diagnostic change
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